Patch 1.25 that just came out is probably for MAC only. It fixes a severe issues Mac Users were seeing with MAC OS X LION and certain graphic cards.
This patch seems to be specifically for this one problem. If you are on a mac and don’t have it, don’t patch for there are reports that people had to reinstall the whole game for the patch to install.
Core Mods for Version 1.24 should be fine with this patch.